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Identification of Epidermal Signatures in Patients With Atopic Dermatitis

NCT02680405 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 50

Last updated 2019-05-10

No results posted yet for this study

Summary

Atopic dermatitis is a skin disorder with an itchy, red skin rash. This may be because certain proteins are increased in the skin of AD patients. The increased expression of these proteins play an important role in the development of AD and may increase the risk for persons with AD to get skin infections and allergies.

There are very few non-invasive ways to diagnose and monitor the development and progression of atopic dermatitis. The goal of this study is to develop laboratory tests, done on skin samples collected by tapy stripping, that can be used for early detection and monitoring the response to treatment for a variety of skin diseases, including atopic dermatitis.

Conditions

Interventions

PROCEDURE

Skin Biopsy

Full thickness skin biopsies will be collected from each subject used for proteomic and genomic analysis of associated biomarker levels.

PROCEDURE

Skin tape stripping

Skin tape stripping used for proteomic and genomic analysis of associated biomarker levels.

PROCEDURE

Blood draw

Whole blood and serum testing used for proteomic and genomic analysis of associated biomarker levels.

Sponsors & Collaborators

  • MedImmune LLC

    collaborator INDUSTRY

  • National Jewish Health

    lead OTHER

Principal Investigators

  • Donald Leung, MD, PhD · National Jewish Health

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2016-04-30
Primary Completion
2016-07-31
Completion
2020-12-31

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02680405 on ClinicalTrials.gov