MedTrace Logo

PMRR-NO: Pulmonary Metabolic Radiation Response Versus Exhaled Nitric Oxide

NCT00867477 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 163

Last updated 2014-08-28

No results posted yet for this study

Summary

The goal of this clinical research study is to use a new breathing test that measures the amount of nitric oxide (NO) you exhale. Researchers want to compare your "NO" levels to the amount of inflammation in your lungs, as measured using a positron emission tomography (PET) scan reading, and with respiratory symptoms questionnaire.

Conditions

  • Gastrointestinal Disease
  • Esophageal Cancer
  • Lung Cancer

Interventions

PROCEDURE

Breathing Test

Exhale into NO breath analyzer for 10 seconds, repeated 3 times (before radiation therapy starts, after completing radiation therapy, and after scheduled PET scan).

BEHAVIORAL

Respiratory Symptoms Questionnaire

3 page questionnaire about breathing and any symptoms experienced, at each of 2 NO breathing tests.

PROCEDURE

Pet Scan

Between 40 and 50 days after the end of the radiation therapy. Ten (10) participants will receive a second PET scan within 2-7 days after the first PET scan in order to check reproducibility.

Sponsors & Collaborators

  • M.D. Anderson Cancer Center

    lead OTHER

Principal Investigators

  • Thomas Guerrero, MD, PhD · UT MD Anderson Cancer Center

Study Design

Allocation
NON_RANDOMIZED
Purpose
SCREENING
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2009-03-31
Primary Completion
2014-08-31
Completion
2014-08-31

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00867477 on ClinicalTrials.gov