Cardiopulmonary Monitoring in Lung Cancer Patients Receiving Combined Thoracic Radiotherapy and Immunotherapy
NCT06410300 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 125
Last updated 2025-06-19
Summary
The overall purpose of this study is to evaluate cardiopulmonary toxicity in patients with lung cancer (NSCLC or SCLC) undergoing combined thoracic radiotherapy ± chemotherapy and immunotherapy through timed monitoring and blood sample collection and to identify correlative biomarkers for predicting cardiopulmonary adverse events.
Conditions
Interventions
- RADIATION
-
Curative Radiotherapy
Radiation dose of 45 Gy or higher
- DRUG
-
Immunotherapy
checkpoint inhibitor per PI discretion
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH -
Bo Lu
lead OTHER
Principal Investigators
-
Bo Lu, MD · Chair, Department of Radiation Oncology
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2024-04-19
- Primary Completion
- 2028-04-19
- Completion
- 2030-04-19
Countries
- United States
Study Locations
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