MedTrace Logo

Heated Humidified Continuous Positive Airway Pressure and Nasal Physiology

NCT00850876 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 20

Last updated 2010-04-09

No results posted yet for this study

Summary

Nasal continuous positive airway pressure can cause nasal side effects which can compromise compliance to therapy. Humidifiers can attenuate this effect. However, the mechanism by which humidified CPAP alleviates nasal symptoms has never been assessed objectively in OSA patients. Therefore, the purpose of this study is to examine the effect of humidified CPAP on nasal airway physiology with combined measurements of nasal resistance and level of inflammatory markers. The investigators' hypothesis is that the addition of heated humidification in CPAP decreases nasal airway resistance and nasal mucosal inflammation markers and thus, ameliorates nasal symptoms of OSAS patients.

Conditions

  • Obstructive Sleep Apnea Syndrome
  • Nasal Obstruction

Sponsors & Collaborators

  • University of Athens

    lead OTHER

Principal Investigators

  • Ioannis Koutsourelakis, MD · 1Center of Sleep Disorders Medical School of Athens University, Department of Critical Care and Pulmonary Services

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2008-09-30
Primary Completion
2009-03-31
Completion
2009-06-30

Countries

  • Greece

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00850876 on ClinicalTrials.gov