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Endometrial Leucocytes Around the Time of Embryo Implantation in Women Undergoing in IVF-ET

NCT04079959 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 120

Last updated 2020-01-23

No results posted yet for this study

Summary

Uterine natural killer (uNK) cells have been implicated to play a role in female reproductive performance. Serval studies showed an increased uNK cell density in the endometrium of women with reproductive failure. In this study, we wish to investigate the density and clustering of four different immune cells.

Conditions

  • Pregnancy Related

Interventions

PROCEDURE

endometrial biopsy

. Endometrial samples are obtained using a biopsy catheter as follows: the Pipette is inserted through the cervical os and advanced gently until resistance is felt. The inner piton of the device is then withdrawn to create suction, and the endometrial sample is obtained by moving the pipette up and down approximately 2-3 cm within the uterine cavity. The device is rotated 360° to ensure adequate coverage of the area.

Sponsors & Collaborators

  • Chinese University of Hong Kong

    lead OTHER

Principal Investigators

  • Xiaoyan Chen, PhD · Chinese University of Hong Kong

Eligibility

Min Age
18 Years
Max Age
40 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-09-15
Primary Completion
2022-12-31
Completion
2023-12-31

Countries

  • Hong Kong

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04079959 on ClinicalTrials.gov