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A Study to Evaluate the Efficacy and Safety of LCI699 Compared to Placebo in Participants With Resistant Hypertension

NCT00817635 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 155

Last updated 2021-06-02

Study results available
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Summary

This study assessed the blood pressure effect, safety and tolerability of LCI699 compared to placebo and eplerenone in participants with resistant hypertension.

Conditions

Interventions

DRUG

LCI699

LCI699 oral capsules

DRUG

Eplerenone

Eplerenone oral capsules

DRUG

LCI699-matching Placebo

LCI699-matching placebo oral capsules

DRUG

Eplerenone-matching Placebo

Eplerenone-matching placebo oral capsules

Sponsors & Collaborators

  • Great Lakes Drug Development, Inc.

    collaborator INDUSTRY

  • Integrium

    collaborator INDUSTRY

  • Novartis

    lead INDUSTRY

Principal Investigators

  • Novartis Pharmaceuticals · Novartis Pharmaceuticals

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2008-12-22
Primary Completion
2009-10-13
Completion
2009-10-13
FDA Drug
Yes

Countries

  • United States
  • Iceland

Study Locations

More Related Trials

Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00817635 on ClinicalTrials.gov