A Study to Determine the Effectiveness and Tolerability of MK8141 in Patients With High Blood Pressure (MK-8141-006)
NCT00543413 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 160
Last updated 2015-10-16
Summary
This study will evaluate the effectiveness and tolerability of MK8141 in lowering blood pressure in patients who have hypertension (high blood pressure).
Conditions
Interventions
- DRUG
-
MK8141
MK8141 250 mg tablet once daily; 500 mg tablet once daily 4 week treatment period
- DRUG
-
Comparator: placebo (unspecified)
MK8141 Pbo tablet once daily. 4 week treatment period.
- DRUG
-
Enalapril
Enalapril 20 mg tablet once daily. 4 week treatment period.
Sponsors & Collaborators
-
Actelion
collaborator INDUSTRY - lead INDUSTRY
Principal Investigators
-
Medical Monitor · Merck Sharp & Dohme LLC
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- DOUBLE
- Model
- PARALLEL
Eligibility
- Min Age
- 35 Years
- Max Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2007-10-31
- Primary Completion
- 2008-06-30
- Completion
- 2008-06-30
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