MedTrace Logo

Saline Solution Versus Voluven®: A Controlled Study of Fluid Resuscitation in Severe Sepsis

NCT00799916 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 30

Last updated 2009-09-15

No results posted yet for this study

Summary

Fluid resuscitation of severe sepsis may consist of natural or artificial colloids or crystalloids. There is no evidence-based support for one type of fluid over another.

The investigators hypothesis is that fluid resuscitation with Voluven® is advantageous to normal saline solution to improve sublingual microcirculation.

Conditions

Interventions

DRUG

Resuscitation (Voluven)

Resuscitation aimed at venous oxygen saturation higher than 70%

DRUG

Resuscitation (Saline)

Resuscitation aimed at venous oxygen saturation higher than 70%

Sponsors & Collaborators

  • Clínica Bazterrica

    collaborator OTHER

  • Sanatorio Otamendi y Miroli

    collaborator UNKNOWN

  • National Agency for Scientific and Technological Promotion, Argentina

    collaborator OTHER

  • Universidad Nacional de La Plata

    lead OTHER

Principal Investigators

  • Arnaldo Dubin, MD · Sanatorio Otamendi y Miroli

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2006-01-31
Primary Completion
2009-08-31
Completion
2009-08-31

Countries

  • Argentina

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00799916 on ClinicalTrials.gov