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Clonidine-Remifentanil. Effect of the Combination on Acute Pain and Respiration in Healthy Volunteers

NCT00730054 · Status: COMPLETED · Phase: PHASE1/PHASE2 · Type: INTERVENTIONAL · Enrollment: 12

Last updated 2011-07-06

No results posted yet for this study

Summary

The hypothesis is that systemic remifentanil and Clonidine act in a synergistic manner to relief acute main in an experimental human pain model. Of interest is also the effect of the combination on respiration, sedation and cognitive behavior.

Conditions

  • Acute Pain
  • Respiration
  • Sedation

Interventions

DRUG

Remifentanil+clonidine

iv Remifentanil+ iv clonidine

Sponsors & Collaborators

  • Oslo University Hospital

    lead OTHER

Principal Investigators

  • Jon B Bergmann, Ass. Prof. · Dep of Anesthesia and Intensive Care, Rikshospitalet-Radiumhospitalet Medical Center

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
50 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2005-02-28
Primary Completion
2005-05-31
Completion
2005-05-31

Countries

  • Norway

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00730054 on ClinicalTrials.gov