MedTrace Logo

Effects of Statins on the Pharmacokinetics for Midazolam in Healthy Volunteers

NCT00716846 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 11

Last updated 2011-09-07

No results posted yet for this study

Summary

The purpose of this study is to investigate whether statins have any influence on cytochrome P450 (CYP) 3A4 enzyme activity using a probe drug midazolam.

Conditions

  • Healthy Volunteers

Interventions

DRUG

simvastatin

10mg, 2 weeks

DRUG

atorvastatin

10mg

DRUG

pitavastatin

2mg

Sponsors & Collaborators

  • Hamamatsu University

    lead OTHER

Principal Investigators

  • Hiroshi Watanabe, MD,PhD · Hamamatsu University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
CROSSOVER

Eligibility

Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2006-06-30
Primary Completion
2008-07-31
Completion
2008-08-31

Countries

  • Japan

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00716846 on ClinicalTrials.gov