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Statins Evaluation in Coronary Procedures and Revascularization Trial

NCT01448642 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 4191

Last updated 2019-06-17

No results posted yet for this study

Summary

The purpose of this study is to determine whether a loading dose of atorvastatin before percutaneous intervention procedures in acute coronary syndromes is effective to reduce major cardiovascular events(MACE).

Conditions

  • Acute Coronary Syndrome

Interventions

DRUG

Atorvastatin

Atorvastatin loading dose of 80mg before PCI, reloading dose of 80mg 24 hours after PCI, and atorvastatin 40mg for 30 days

DRUG

Placebo

Matching placebo before PCI and 24 hours after PCI. Atorvastatin 40mg for 30 days

Sponsors & Collaborators

  • Ministry of Health, Brazil

    collaborator OTHER_GOV

  • Hospital do Coracao

    lead OTHER

Principal Investigators

  • Otavio Berwanger · Hospital do Coracao

  • Renato D Lopes, MD, PhD · Brazilian Clinical Research Institute

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2012-04-30
Primary Completion
2017-11-30
Completion
2018-04-30

Countries

  • Brazil

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01448642 on ClinicalTrials.gov