Atorvastatin is a statin lipid-lowering medicine widely used to treat dyslipidemia and reduce cardiovascular risk. It is marketed under brand names including Lipitor and is taken orally. It has been approved in the U.S. since 1996 and is available as a generic prescription drug.
A systematic review found strong FAERS signals linking labetalol to rare liver injury, while a case report describes hyperacute liver failure from high-dose atorvastatin that resolved after discontinuation.
A major meta-analysis of 19 randomized trials involving 123,940 participants found that only six side effects are actually caused by statins, challenging long-standing concerns about the drugs' safety profile.
A 30-year-old female with stage IV gallbladder adenocarcinoma achieved complete metabolic resolution of metastases after three cycles of pembrolizumab, gemcitabine, and cisplatin, despite presenting without traditional risk factors.
| NCT ID | Title | Status | Phase |
|---|---|---|---|
| NCT07762105 |
Study of Atorvastatin and Its Effects in Clinical and Radiological Aspects in Patients With Moderate-to-Severe Thyroid Eye Disease |
NOT_YET_RECRUITING | PHASE1 |
| NCT07727681 |
Perioperative Statins to Prevent AFib After Lung Surgery |
RECRUITING | PHASE4 |
| NCT07717788 |
Therapeutic Prospects of HMG-CoA Reductase Inhibitors, Atorvastatin and Rosuvastatin, in Osteoporotic Patients |
COMPLETED | NA |
| NCT07680595 |
Prospective Management of Plaque Instability With Statins and Extra Folic Acid |
RECRUITING | PHASE1/PHASE2 |
| NCT07668076 |
The Potential Cardioprotective Effect of Addition of Atorvastatin in Breast Cancer Patients |
COMPLETED | PHASE2 |
| NCT07630363 |
PTC-Guided Atorvastatin Plus Axitinib and Toripalimab in Advanced RCC |
NOT_YET_RECRUITING | PHASE1/PHASE2 |
| NCT07624604 |
Evaluation of the Therapeutic Efficacy of Auricular Pellets Combined With Atorvastatin 20mg in Patients With Dyslipidemia and Phlegm-Dampness Syndrome |
NOT_YET_RECRUITING | NA |
| NCT07586540 |
Alirocumab for Stabilisation of Symptomatic Vulnerable Carotid Plaque |
NOT_YET_RECRUITING | PHASE3 |
| NCT07568574 |
Impact of Medically Supervised Performance-Enhancing Substances (PES) on Elite Athletes |
ENROLLING_BY_INVITATION | NA |
| NCT07534592 |
A Study to Investigate the Effect of Elecoglipron on Rosuvastatin and Atorvastatin in Healthy Participants |
ACTIVE_NOT_RECRUITING | PHASE1 |
