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Ultraviolet Exposure, Antioxidant Use and Skin Erythema at Extreme High Altitude

NCT00685438 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 25

Last updated 2008-05-28

No results posted yet for this study

Summary

With the increasing tourism and adventure travel into extreme environments comes the need to reassess the required protection against ultraviolet (UV) radiation and possible other oxidative stresses. This is an observational study of UV radiation exposure and skin erythema while at extreme altitude (Mt. Everest). In addition to UV exposure, skin erythema, antioxidant use (such as vitamins C and E) will be measured.

Hypothesis:

1. UV radiation at extreme altitude has larger effects on the skin than at sea level; therefore requiring an adjustment of the antioxidant use for adequate protection.
2. The skin is an accurate reflection of UV and oxidative stress exposure
3. The efficacy of oxidatives stress is reflective of the ethnicity of the individual.

Conditions

  • Altitude
  • Ultraviolet Rays
  • Antioxidants
  • Oxidative Stress
  • Erythema

Sponsors & Collaborators

  • Ontario Centres of Excellence

    collaborator INDUSTRY

  • Sunnybrook Health Sciences Centre

    lead OTHER

Principal Investigators

  • Ivy S Cheng, MD · Sunnybrook Hospital Emergency Department

  • Lothar D Lilge, PhD · Ontario Cancer Institute

Eligibility

Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2007-04-30
Completion
2007-06-30

Countries

  • Nepal

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00685438 on ClinicalTrials.gov