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Effect of Pre-cooling on Whole-body Heat Loss During Exercise-heat Stress

NCT06670339 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 10

Last updated 2025-06-17

No results posted yet for this study

Summary

Endurance exercise performance declines in hot environments as core body temperature increases. To enhance performance, body pre-cooling strategies, such as cold-water immersion have been employed to lower resting core temperature thereby increasing the body's heat storage capacity. In turn, the increase in body core temperature associated with exercise in the heat is blunted, allowing the individual to exercise at higher intensity and or for a longer period of time. However, the mechanisms by which pre-cooling impacts heat exchange during exercise remain unclear. While existing research has focused on the performance benefits of pre-cooling the body, relatively little is known about the impacts of pre-cooling on whole-body heat exchange during an exercise-heat stress. Investigators will therefore evaluate whole-body heat exchange (dry ± evaporative heat loss as assessed using a direct air calorimeter) during a prolonged (1-hour) moderate-intensity cycling bout in the heat (wet-bulb globe temperature of 29°C; equivalent to 37.5°C, 35% relative humidity) performed with and without pre-cooling by cool-water (\~17°C) immersion.

Conditions

  • Thermoregulation
  • Cold Exposure
  • Heat Stress
  • Exercise

Interventions

OTHER

No Cooling

Participants will not be pre-cooled prior to completing a 60-minute moderate-intensity exercise bout in the heat.

OTHER

Pre-Cooling

Participants will be immersed in cold (\~17°C) water to elicit a decrease in rectal temperature by 0.5°C from baseline values prior to completing a 60-min moderate-intensity exercise bout in the heat.

Sponsors & Collaborators

  • University of Ottawa

    lead OTHER

Principal Investigators

  • Glen P Kenny, PhD · University of Ottawa

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
30 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2024-10-24
Primary Completion
2025-02-27
Completion
2025-02-27

Countries

  • Canada

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06670339 on ClinicalTrials.gov