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Daily Sedative Interruption in Critically Ill Patients Being Managed With a Sedation Protocol.

NCT00675363 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 410

Last updated 2025-05-09

No results posted yet for this study

Summary

The purpose of this study is to determine whether the use of both a nurse-driven sedation protocol and daily sedative interruption, compared with a sedation protocol alone, result in better outcomes for mechanically ventilated adults.

Conditions

  • Critical Illness

Interventions

PROCEDURE

Protocolized Sedation

Nurse-directed protocol for administering sedation and/or analgesia.

PROCEDURE

Protocolized sedation, with daily interruption

Nurse-directed protocols for administering sedation and/or analgesia, with daily interruption of sedation/analgesia

Sponsors & Collaborators

  • Canadian Institutes of Health Research (CIHR)

    collaborator OTHER_GOV

  • Ottawa Hospital Research Institute

    collaborator OTHER

  • Mount Sinai Hospital, Canada

    lead OTHER

Principal Investigators

  • Sangeeta Mehta, M.D. · MOUNT SINAI HOSPITAL

Study Design

Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2008-01-31
Primary Completion
2011-08-31
Completion
2012-10-17

Countries

  • United States
  • Canada

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00675363 on ClinicalTrials.gov