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Effects of Melatonin and Oxygen Consumption and Choroidal Blood Flow

NCT00675181 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 16

Last updated 2012-09-11

No results posted yet for this study

Summary

Does melatonin affect basal metabolic rate, increase choroidal blood flow and reduce the vasospastic syndrome (VS)?

The main questions are:

Do women with VS exhibit...

* a different basal metabolic rate
* a reduced choroidal blood flow
* a reduced increase of oxygen consumption after intake of ice-water
* a different oxygen consumption after melatonin intake
* a different choroidal blood flow after melatonin intake
* a different oxygen consumption after melatonin intake and after intake of ice-water….?

Conditions

  • Vasospastic Syndrome

Interventions

DRUG

Placebo

per os

DRUG

Melatonin

5mg per os

Sponsors & Collaborators

  • University Hospital, Basel, Switzerland

    lead OTHER

Principal Investigators

  • Selim Orguel, MD · University Eye Clinic, Basel, Switzerland

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
TRIPLE
Model
CROSSOVER

Eligibility

Min Age
20 Years
Max Age
30 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2008-05-31
Primary Completion
2010-01-31
Completion
2010-01-31

Countries

  • Switzerland

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00675181 on ClinicalTrials.gov