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Melatonin and Cardiac Outcome After Major Surgery

NCT00315926 · Status: COMPLETED · Phase: PHASE2/PHASE3 · Type: INTERVENTIONAL · Enrollment: 52

Last updated 2010-06-30

No results posted yet for this study

Summary

The purpose of this study is to assess whether treatment with melatonin can reduce cell damage and inflammatory stress response and thereby occurrence of myocardial injury after abdominal aortic surgery.

Conditions

  • Aortic Aneurysm

Interventions

DRUG

Melatonin

Melatonin 50 mg during surgery and 10 mg every night for 3 nights

DRUG

Placebo

a mixture of ethanol and physiological saline

Sponsors & Collaborators

  • University Hospital, Gentofte, Copenhagen

    lead OTHER

Principal Investigators

  • Bülent Kücükakin · Department of Surgical Gastroenterology, University Hospital of Copenhagen in Gentofte

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2007-01-31
Primary Completion
2008-07-31
Completion
2008-07-31

Countries

  • Denmark

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00315926 on ClinicalTrials.gov