Adiponectin in Obese Women With T2DN and Effects by RAS Blocker
NCT00561704 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 80
Last updated 2007-11-21
Summary
Insulin resistance typically characterizes type 2 diabetes (T2DM) and prediabetic states and is the prominent feature of the metabolic syndrome.Adiponectin plays an important part in glucose metabolism,insulin resistance, the deterioration of renal function.we hypothesize there is a difference serum adiponectin levels between obese and non-obese women with type 2 diabetic nephropathy. Furthermore, these two groups would respond difference to the RAs blocker(Losartan).
Conditions
- Obese
- Type 2 Diabetes
- Diabetic Nephropathy
- Glucose Metabolism
- Angiotensin II Type 1 Receptor Blockers
Interventions
- DRUG
-
losartan
losartan, 100mg daily,
Sponsors & Collaborators
-
Shanghai Jiao Tong University School of Medicine
lead OTHER
Principal Investigators
-
hui min Jin, MD · shanghai No 3 people's hospital
Study Design
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 30 Years
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2007-04-30
- Completion
- 2007-10-31
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