Comprehensive Clinical Evaluation Study of GLP-1RA

Summary

The objective of this project is to identify the most efficacious glucagon-like peptide-1 receptor agonists (GLP-1RAs) for the treatment of adult patients with type 2 diabetes mellitus (T2DM). In accordance with the index system and evaluation rules set forth in the Management Guidelines for Comprehensive Clinical Evaluation of Drugs, the effects of GLP-1RAs drugs in real-world settings are tracked, summarised, and analysed across six dimensions: safety, effectiveness, economy, innovation, appropriateness, and accessibility. This is done with the objective of ensuring that these drugs are fully utilised in accordance with their potential benefits. The objective is to ascertain the role of medical institutions as the principal entity responsible for the comprehensive evaluation of the clinical application of drugs and to provide data that will reduce the risk of using GLP-1RAs drugs. Moreover, the objective is to ascertain the advantages of their clinical application and to guarantee the safe and rational use of drugs for patients with type 2 diabetes mellitus. The objective of this study is to facilitate the fulfilment of medical institutions' role as the primary entity responsible for the comprehensive evaluation of the clinical application of medicines. Furthermore, the study will provide data that can be used to reduce the risk of using GLP-1RAs drugs, explore the advantages of their clinical application, and guarantee the safe and rational use of medicines for patients with type 2 diabetes.

Conditions

• T2DM

Sponsors & Collaborators

• LI YAN

  lead OTHER

Principal Investigators

• Yining Dong, pharmacist · Shandong Third Hospital

• Zhongming Wu, doctor · Endocrine and Metabolic Disease Hospital of Shandong First Medical University

• Yue Liu, pharmacist · Shandong University of Traditional Chinese Medicine

• Dandan Wu, pharmacist · Affiliated Hospital of Binzhou Medical College

• Jing Peng, pharmacist · Jining Medical University

• Qi Wang, pharmacist · Jinan Fifth People's Hospital

• Zhaohui Meng, pharmacist · Jinan Laiwu People's Hospital

• Dong wei Wang, doctor · Jinan Mental Health Center

• Zhong Yuan, pharmacist · Jinan Municipal Hospital

• Ming Xue, pharmacist · Jinan Hospital, Guang'anmen Hospital, China Academy of Traditional Chinese Medicine, China

• Jing Lin, pharmacist · Shijhong District People's Hospital

• Xingshan Wang, doctor · Changqing District Hospital of Traditional Chinese Medicine

• Min Fan, pharmacist · Pingyin County People's Hospital

• Xue Zheng, pharmacist · Zibo Center Hospital

• Ming Xu, pharmacist · Zibo First Hospital

• Yan Song, pharmacist · Zibo Municipal Hospital

• Ruoxun Liu, pharmacist · Zibo Hospital of Traditional Chinese Medicine

• Qing Zhao, doctor · Linzi District Maternal and Child Health Center

• Zhenwei Chen, pharmacist · Yiyuan County People's Hospital

• Zhiyan Li, pharmacist · Zaozhuang Municipal Hospital

• Shenling Cheng, pharmacist · Tengzhou Central People's Hospital

• Qixia Zhao, pharmacist · Zaozhuang Shanting District People's Hospital

• Jintang Ning, pharmacist · Dongying People's Hospital

• Juying Ding, pharmacist · Shengli Oilfield Hospital

• Jiaxi Jiang, pharmacist · Haiyang People's Hospital

• Guichun Wang, pharmacist · Longko People's Hospital

• Zhentian Cheng, pharmacist · Weifang Yidu Center Hospital

• Yueliang Ji, doctor · Fangzi District People's Hospital

• Donglou Liang, pharmacist · Jining First People's Hospital

• Li Zhang, pharmacist · QuFu People's Hospital

• Guifeng Tan, doctor · Wenshang County People's Hospital

• Ronghua Wang, pharmacist · Weihai Maternal and Child Health Center

• Jianfang Liu, pharmacist · Rizhao People's Hospital

• Xiangju Tian, doctor · Linyi Hospital of Traditional Chinese Medicine

• Pengcheng Du, pharmacist · Shandong University Qilu Hospital, Dezhou Hospital

• Fujian Xu, pharmacist · Heze Municipal Hospital

• Deping Ho, pharmacist · Heze Third People's Hospital

• Jingyong Xue, pharmacist · Heze Mudan People's Hospital

• Lishun Yin, pharmacist · Heze Dingtao District People's Hospital

• Shengmei Wei, pharmacist · Caoxian People's Hospital

• Jing Meng, pharmacist · Shanxian Central Hospital

• Ye Fan, pharmacist · Yuncheng County People's Hospital

• Jingjing Zhang, pharmacist · Qingdao Eighth People's Hospital

• Wenqian Han, pharmacist · Tai'an Central Hospital

• Wenwen Lv, pharmacist · Affiliated Hospital of Binzhou Medical College

• Tao Geng, pharmacist · The Second Affiliated Hospital of Shandong First Medical University

• Fang Liu, pharmacist · Shengli Oilfield Hospital

• Congrong Wang, pharmacist · Shandong Public Health Clinical Center

• Ping Wang, pharmacist · Tengzhou Central People's Hospital

• Yuxia Gao, pharmacist · Dongying Hospital Affiliated to Shandong University of Traditional Chinese Medicine (Dongying Hospital of Traditional Chinese Medicine)

• Bo Liu, pharmacist · Qingdao Central Hospital

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2024-07-01

Primary Completion

2025-12-31

Completion

2026-07-31

Countries

• China

Study Locations