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Genetic- and Biological-Markers of Predisposition to Atherosclerosis: Leipzig-Heart Study

NCT00497887 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 4000

Last updated 2010-10-19

No results posted yet for this study

Summary

Atherosclerotic cardiovascular disease is the major cause of morbidity and mortality in Western societies. It is a complex genetic disorder with many genes involved and significant gene-environment interactions. The aim of the study is to identify novel genetic- and biological-markers of atherosclerosis. Atherosclerosis is assessed in the coronary arteries using coronary angiography as well as in the carotid artery (intima-media-thickness) and peripheral vessels (ankle brachial index). Association analysis of genetic and metabolic markers with atherosclerotic burden will be performed to identify novel factors of disposition to atherosclerotic vascular disease.

Conditions

  • Atherosclerosis
  • Coronary Arteriosclerosis
  • Carotid Artery Diseases
  • Genetic Predisposition to Disease
  • Biological Markers

Sponsors & Collaborators

  • University of Leipzig

    lead OTHER

Principal Investigators

  • Joachim Thiery, MD PhD · University of Leipzig

Eligibility

Min Age
18 Years
Max Age
85 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2006-12-31

Countries

  • Germany

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00497887 on ClinicalTrials.gov