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Impact of Polymorphism on Pulmonary Pressure in Subjects With Pulmonary Hypertension of Different Cause

NCT00893178 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 350

Last updated 2021-11-17

No results posted yet for this study

Summary

Pulmonary Hypertension (PH) is a disease that is characterized by vasoconstriction of small vessels of the lung. Many cases do have proliferation of endothelial cells within these vessels. A possible influence of polymorphisms of genes relevant for inflammatory and endothelial processes is suspected.

Especially patients with chronic heart failure can develope PH. The reasons therefore are lacking.

The researchers investigate different polymorphism and the influence of these on pulmonary artery pressure (measured invasively) in patients with congestive heart failure (CHF) and patients with primary pulmonary hypertension.

Conditions

  • Congestive Heart Failure
  • Pulmonary Hypertension

Sponsors & Collaborators

  • Heart Center Leipzig - University Hospital

    collaborator OTHER

  • University of Leipzig

    lead OTHER

Principal Investigators

  • Sven Möbius-Winkler, M.D · University Leipzig-Heart Center

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2007-12-31
Primary Completion
2021-11-30
Completion
2021-11-30

Countries

  • Germany

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00893178 on ClinicalTrials.gov