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Genetic Linkage Study of Idiopathic Talipes Equinovarus (ITEV) (Clubfoot)

NCT00474344 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 370

Last updated 2022-05-18

No results posted yet for this study

Summary

The goal of this study is to identify and characterize the genetic loci causing idiopathic talipes equinovarus (clubfoot).

The hypothesis is that a few genes account for a substantial fraction of ITEV and that these genes can be identified in defined populations. Towards this goal, in preliminary studies, Dr. Hecht's group has identified two genes, NAT2 and CASP10, which demonstrate evidence for linkage and association to ITEV.

Conditions

  • Clubfoot

Sponsors & Collaborators

  • National Institutes of Health (NIH)

    collaborator NIH

  • Shriners Hospitals for Children

    collaborator OTHER

  • University of British Columbia

    lead OTHER

Principal Investigators

  • Christine Alvarez, MD · University of British Columbia

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2004-08-31
Primary Completion
2010-12-31
Completion
2013-08-31

Countries

  • United States
  • Canada

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00474344 on ClinicalTrials.gov