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Young Pectus Excavatum Patients and Genetic Defects

NCT05443113 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 18

Last updated 2022-07-05

No results posted yet for this study

Summary

In most pectus excavatum (PE) patients an underlying genetic defect is not found with molecular analysis, as a direct genetic link with PE has yet to be found and because potential underlying genetic disorders are quite rare. Only one-fifth of all PE cases are identified in the first decade of life and thus of congenital origin making younger PE patients a unique patient group. Therefore, the research question is; is early-onset pectus excavatum (PE) more likely to be part of a genetic defect than PE which became apparent during puberty or adolescence?

Conditions

Interventions

DIAGNOSTIC_TEST

Genetic analysis

Genetic analysis by geneticists

Sponsors & Collaborators

Principal Investigators

  • René M Wijnen · Erasmus Medical Center

Eligibility

Min Age
0 Years
Max Age
11 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-09-01
Primary Completion
2020-10-01
Completion
2020-10-01

Countries

  • Netherlands

Study Locations

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Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05443113 on ClinicalTrials.gov