MedTrace Logo

Ocular Surface Changes in Patients With Cystic Fibrosis

NCT00345280 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 26

Last updated 2008-06-17

No results posted yet for this study

Summary

Cystic fibrosis(CF) is an inherited disease affecting children, adolescents and young adults with dysfunction of secretory glands.It is caused by mutations in the protein-coding gene which function as the cystic fibrosis transmembrane regulator (CFTR), responsible for the secretion of chloride ions in epithelial cells, adenocytes, sweat gland cells, pancreatic ducts,alimentary and respiratory tracts and eye. Assessment of the relationship between the inflammatory processes and apoptosis in the eye in the course of cystic fibrosis will allow determination of immunological exponents which may facilitate diagnosis.

Conditions

  • Eye Manifestations

Interventions

PROCEDURE

impression cytology, obtain the tear fluid

Vitamin A

Sponsors & Collaborators

  • University of Bialystok

    lead OTHER_GOV

Principal Investigators

  • Malgorzata Mrugacz, MD, PhD · Department of Pediatric Ophthalmology Medical University of Bialystok, Poland

Eligibility

Min Age
3 Years
Max Age
25 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2006-08-31
Completion
2008-09-30

Countries

  • Poland

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00345280 on ClinicalTrials.gov