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Muscle Endurance in Children With Cystic Fibrosis

NCT06812793 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 48

Last updated 2026-01-06

No results posted yet for this study

Summary

Cystic fibrosis (CF) is a genetic disorder affecting exocrine glands, leading to thick, viscous secretions that damage organs such as the lungs, pancreas, and reproductive system. Respiratory failure from CF lung disease is a major cause of morbidity and mortality, with chronic inflammation and infections disrupting mucociliary clearance. This results in declining respiratory functions, muscle strength, physical inactivity, and quality of life. While some studies compare respiratory and lower extremity muscle endurance in children with CF, none have evaluated core muscle endurance. This study aims to compare respiratory muscle strength, endurance, and muscle endurance in the core and lower extremities between children with CF and healthy peers.

Conditions

Interventions

OTHER

Measurement of Core Muscle Endurance

Endurance of the flexor, extensor and lateral trunk muscles will be assessed using the McGill Trunk Endurance Tests.

OTHER

Respiratory Muscle Strength

Inspiratory and expiratory muscle strength will be made with a portable, electronic intra-oral pressure measuring device.

OTHER

Respiratory Muscle Endurance

Respiratory muscle endurance testing will be measured using an inspiratory muscle training device at increasing threshold load.

OTHER

Peripheral Muscle Endurance

Peripheral muscle endurance will be assessed by performing 30 and 60 second sit-to-stand tests.

Sponsors & Collaborators

  • Bezmialem Vakif University

    lead OTHER

Eligibility

Min Age
6 Years
Max Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2025-02-05
Primary Completion
2025-11-03
Completion
2025-12-29

Countries

  • Turkey (Türkiye)

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06812793 on ClinicalTrials.gov