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Hyperpolarized Xenon MRI in Cystic Fibrosis Pulmonary Exacerbations

NCT02606487 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 21

Last updated 2018-10-04

No results posted yet for this study

Summary

The investigators aim to assess whether pulmonary MRI (hyperpolarised 129Xe ventilation imaging \[Xe-MRI\]) can detect changes in ventilation defects in patients with CF before and after treatment for a pulmonary exacerbation. The investigators will determine whether changes seen using pulmonary Xe-MRI are associated with changes in pulmonary function (spirometry, lung volumes, lung clearance index \[LCI\]) in patients with CF before and after pulmonary exacerbation.

Conditions

Sponsors & Collaborators

  • The Hospital for Sick Children

    lead OTHER

Principal Investigators

  • Felix Ratjen, MD PhD · The Hospital for Sick Children

Eligibility

Min Age
8 Years
Max Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2015-11-30
Primary Completion
2017-11-30
Completion
2017-11-30

Countries

  • Canada

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02606487 on ClinicalTrials.gov