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Banding Versus Propranolol for Primary Prophylaxis of Variceal Bleeding

NCT00337740 · Status: TERMINATED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 120

Last updated 2012-04-23

No results posted yet for this study

Summary

Whether beta-blockers or banding is the best therapy for primary prophylaxis of variceal bleeding is subject to debate. A randomized comparison between the two treatments was performed in candidates for liver transplantation. Patients with Child B and C cirrhosis with high risk varices and no previous variceal bleeding are randomized to propranolol or variceal bleeding. Primary end point is variceal bleeding

Conditions

Interventions

PROCEDURE

endoscopic variceal banding

DRUG

propranolol

Sponsors & Collaborators

  • University of Padova

    lead OTHER

Principal Investigators

  • Lorenzo Norberto, prof, M.D. · University of Padova, Department of Surgical and Gastroenterological Sciences, 1st Surgical Clinic

  • Umberto Cillo, prof. M.D. · University of Padova, Department of Surgical and Gastroenterological Sciences, 1st Surgical Clinic

  • Francesco Grigoletto, prof, M.D. · Biostatistic and Epidemiology Unit, Department of Enviromental Medicine and Public Health, University of Padova, Italy

  • Davide D'Amico, prof, MD · Padova University, Department of Surgical and Gastroenterological Sciences, 1st Surgical Clinic

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Countries

  • Italy

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00337740 on ClinicalTrials.gov