Effect of Betablocker or Aldosterone Antagonist Therapy on Patients With Liver Cirrhosis
NCT00332904 · Status: UNKNOWN · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 22
Last updated 2010-06-04
Summary
The study´s purpose is to investigate the effect of beta blockade or aldosterone antagonist therapy on oxygenation, peripheral and cardiac hemodynamics and humoral systems, in patients with liver cirrhosis.
Conditions
- Liver Cirrhosis
- Portal Hypertension
Interventions
- DRUG
-
propranolol
tablet 80 mg pr. day in a period of 3 weeks, evt. dose adjustment
- DRUG
-
spironolactone
tablet 200 mg pr. day in 3 weeks, evt. dose adjustment
Sponsors & Collaborators
-
Hvidovre University Hospital
lead OTHER
Principal Investigators
-
Soeren Moeller, MD, DMSc · Hvidovre University Hospital
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2006-08-31
- Primary Completion
- 2008-07-31
- Completion
- 2010-12-31
Countries
- Denmark
Study Locations
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