The Role of Peptide YY (PYY)in Inhibiting Food Intake.
NCT00259233 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 24
Last updated 2009-01-21
Summary
12 obese subjects will receive peripheral administration of placebo and 4 escalating doses of PYY1-36 and another 12 obese subjects will receive peripheral administration of placebo and 4 escalating doses PYY3-36 on 5 different test days within one week. The patients will be tested in a single blinded dose escalating protocol. Measurements of appetite, ad libitum energy intake, blood pressure and blood sampling will be performed during the test day.
Conditions
Interventions
- DRUG
-
peripheral Peptide YY administration
Sponsors & Collaborators
-
Aditech Pharma AB
collaborator INDUSTRY -
University of Copenhagen
lead OTHER
Principal Investigators
-
Arne Astrup, Professor · Department of Human Nutrition, RVAU
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- SINGLE
- Model
- CROSSOVER
Eligibility
- Min Age
- 20 Years
- Max Age
- 50 Years
- Sex
- MALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2005-03-31
- Completion
- 2005-05-31
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