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A Study To Investigate Markers Of Inflammation In Rheumatoid Arthritis

NCT00242853 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 48

Last updated 2008-10-13

No results posted yet for this study

Summary

This study is being conducted to validate various biomarkers in patients with RA with varying levels of disease severity. Subjects with a diagnosis of rheumatoid arthritis (RA) will be included as controls. The sudy will measure the baseline levels and the intra- and inter-subject variability of exhaled nitric oxide (NO) in patients with inactive/mild and moderate/severe RA on stable therapy or during a course glucocorticoids. In addition exhaled NO levels will be correlated with intra-articular inflammation (power Doppler ultrasonography) as well as markers of systemic inflammation (CRP, ESR).

Conditions

Interventions

PROCEDURE

Power doppler ultrasonography

PROCEDURE

High frequency ultrasonography

PROCEDURE

Exhaled nitric oxide assessment

Sponsors & Collaborators

Principal Investigators

  • GSK Clinical Trials, MD · GlaxoSmithKline

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2004-10-31

Countries

  • United Kingdom

Study Locations

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Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00242853 on ClinicalTrials.gov