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A Study of the Effects of Oral Prednisone in Patients With Rheumatoid Arthritis (MK0000-088)

NCT00746512 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 45

Last updated 2015-05-29

Study results available
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Summary

The study will compare the effects of prednisone vs placebo on synovial blood flow and overall DAS (disease activity score) in patients with rheumatoid arthritis.

Conditions

Interventions

DRUG

Prednisone 15 mg

Prednisone 15 mg tablets once daily for 15 days.

DRUG

Placebo Tablets

Prednisone placebo tablets once daily for 15 days.

DRUG

Prednisone 7.5 mg

Prednisone 7.5 mg over-encapsulated tablets once daily for 15 days

DRUG

Placebo Over-Encapsulated Tablets

Prednisone 7.5 mg placebo over-encapsulated tablets once daily for 15 days

Sponsors & Collaborators

Principal Investigators

  • Medical Monitor · Merck Sharp & Dohme LLC

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2008-09-30
Primary Completion
2009-09-30
Completion
2009-09-30

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Entities

Diseases
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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00746512 on ClinicalTrials.gov