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Citrate Versus Heparin Anticoagulation in Continuous Venovenous Hemofiltration

NCT00209378 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 139

Last updated 2013-04-04

No results posted yet for this study

Summary

The purpose of this study is to compare citrate regional anticoagulation with systemic heparinization in continuous venovenous hemofiltration. The investigators' hypothesis is, that regional citrate anticoagulation with replacement solution containing trisodium citrate, will be associated with lower mortality and less bleeding complications compared to heparin, with also a better filter survival.

Conditions

Interventions

OTHER

regional anticoagulation with citrate

Regional anticoagulation with trisodium citrate is compared with standard systemic heparinization.

OTHER

HfCitPre

regional anticoagulation with citrate containing replacement solution

Sponsors & Collaborators

  • Dirinco B.V.

    collaborator INDUSTRY

  • Free University Medical Center

    lead OTHER

Principal Investigators

  • Piet M ter Wee, MD, PhD · Amsterdam UMC, location VUmc

  • Johan Groeneveld, MD, PhD · Amsterdam UMC, location VUmc

  • Shaikh A Nurmohamed, MD · Amsterdam UMC, location VUmc

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2005-05-31
Primary Completion
2012-05-31
Completion
2012-05-31

Countries

  • Netherlands

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00209378 on ClinicalTrials.gov