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Elimination of Antibiotics During Renal Replacement Therapy and Cytosorb Adsorptive Therapy

NCT02611271 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 30

Last updated 2020-05-07

No results posted yet for this study

Summary

Cytokine adsorption using the cytosorb adsorber is currently investigated to reduce the levels of proinflammatory cytokines in patients with severe sepsis and septic shock. The adsorber is frequently used in series with continuous renal replacement therapy. Up to date, no data on the removal of antibiotic drugs during combined renal replacement therapy and cytokine adsorptive therapy is available. Therefore, we want to investigate

\- whether and to what extent antibiotic drugs (piperacillin/tazobactam and imipenem/cilastatin) are removed during combined continuous renal replacement therapy and cytosorb adsorption in patients with severe sepsis and septic shock

Conditions

Interventions

OTHER

Monitoring of antibiotic drug removal

No study specific intervention will be performed

Sponsors & Collaborators

  • Heinrich-Heine University, Duesseldorf

    lead OTHER

Principal Investigators

  • Detlef Kindgen-Milles, Prof. · Department of Anesthesiology, Duesseldorf University Hospital

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2017-12-01
Primary Completion
2020-08-31
Completion
2020-12-31

Countries

  • Germany

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02611271 on ClinicalTrials.gov