The Potential of Sperm Retrieved by Micro-TESE to Fertilize Vitrified/Warmed Oocytes
NCT03809026 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 100
Last updated 2023-11-02
Summary
Couples referred for microdissection-TESE (m-TESE) due to Klinefelter's syndrome, maturation stop in the spermatogenesis, or failed retrieval of testicular spermatozoa by conventional techniques with needle or TruCut are included. The women are stimulated with FSH in IVF protocols and the aspirated oocytes vitrified with usual applied techniques. Fresh sperm retrieved by micro-TESE are used for fertilization of the warmed oocytes. when it is not possible to obtain testicular sperm, the couples are offered fertilization with warmed oocytes.
Fertilization, cleavage, implantation and pregnancy rates using sperm from the patients versus from sperm donors will be compared.
Conditions
- Azoospermia, Nonobstructive
Sponsors & Collaborators
-
Odense University Hospital
lead OTHER
Eligibility
- Min Age
- 18 Years
- Max Age
- 100 Years
- Sex
- MALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2015-09-01
- Primary Completion
- 2023-12-31
- Completion
- 2024-06-30
Countries
- Denmark
Study Locations
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