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Prevention of Ectopic Bone Related Pain and Disability After Hip Replacement Surgery With Peri-Operative Ibuprofen

NCT00145730 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 1000

Last updated 2006-11-29

No results posted yet for this study

Summary

The primary aim of this randomised trial is to determine the effects of a short peri-operative course of treatment with a non-steroidal anti-inflammatory drug (NSAID), ibuprofen, on the long-term consequences of ectopic bone formation in patients undergoing elective total hip replacement surgery. The specific hypotheses to be tested at that 6 to 12 months after surgery, patients assigned post-operative ibuprofen will have less self-reported pain and physical disability, greater health-related quality of life and reduced ectopic bone formation compared with those assigned placebo.

Conditions

  • Osteoarthritis, Hip
  • Arthroplasty, Replacement, Hip
  • Arthritis, Rheumatoid

Interventions

DRUG

Ibuprofen

Sponsors & Collaborators

  • National Health and Medical Research Council, Australia

    collaborator OTHER

  • Medical Benefits Fund Australia Pty Ltd

    collaborator UNKNOWN

  • The George Institute

    lead OTHER

Principal Investigators

  • Marlene H Fransen, PhD, MPH · The George Institute, University of Sydney

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Model
PARALLEL

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2002-02-28
Completion
2004-05-31

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00145730 on ClinicalTrials.gov