MedTrace Logo

Use of Etoricoxib Compared to Diclofenac in the Perioperative Treatment of Patients After Total Hip Arthroplasty

NCT01229774 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 100

Last updated 2014-09-15

No results posted yet for this study

Summary

The primary aim of this study is to test if etoricoxib decreases the perioperative blood loss compared to diclofenac.

Secondary questions to be explored are:

* Does etoricoxib prevent Heterotopic ossification after Total Hip Arthroplasty as well as diclofenac ?
* Do diclofenac and etoricoxib both reduce pain at rest and on movements?
* Does etoricoxib compared to diclofenac reduce the amount of rescue medication (Oxycodon)?
* Does etoricoxib improve gastrointestinal tolerability compared to diclofenac?

Conditions

  • Coxarthrosis
  • Arthroplasties Hip Replacement
  • Perioperative Blood Loss

Interventions

DRUG

Etoricoxib

Arcoxia 90 mg once a day in the evening day -1 and 0 and once a day in the morning days 1-7 plus on tablett of placebo every evening

DRUG

Diclofenac

Voltaren Resinat 75mg once a day on day -1 and 0 in the evening; twice a day (in the morning and in the evening) days 1-7

Sponsors & Collaborators

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
55 Years
Max Age
85 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2011-02-28
Primary Completion
2014-08-31
Completion
2014-08-31

Countries

  • Germany

Study Locations

More Related Trials

Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01229774 on ClinicalTrials.gov