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Preemptive Analgesia Combination of Celecoxib and Pregabalin in THA

NCT05509946 · Status: UNKNOWN · Phase: PHASE2/PHASE3 · Type: INTERVENTIONAL · Enrollment: 30

Last updated 2022-08-24

No results posted yet for this study

Summary

This is a double-blinded randomized controlled trial aims to evaluate the effect of preemptive analgetic combination of celecoxib and pregabalin to acute pain after total hip arthroplasty. This study will be conducted in Cipto Mangunkusumo Hospital, Jakarta, Indonesia, from October 2022 to April 2023. The subject of this study is adult patient who will be performed total hip arthroplasty.

Conditions

  • Arthroplasty Complications
  • Analgetic
  • Celecoxib
  • Pregabalin

Interventions

DRUG

Single dose of celecoxib 400 mg and pregabalin 150 mg

Single dose of celecoxib 400 mg and pregabalin 150 mg

DRUG

Repeated dose of celecoxib 200 mg and pregabalin 75 mg

Repeated dose of celecoxib 200 mg and pregabalin 75 mg started 3 days before surgery

DRUG

Placebo

Placebo

Sponsors & Collaborators

  • Indonesia University

    lead OTHER

Principal Investigators

  • Andri MT Lubis · Department of Orthopaedic and Traumatology, Faculty of Medicine, Universitas Indonesia

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2022-10-01
Primary Completion
2023-04-01
Completion
2023-04-30

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Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05509946 on ClinicalTrials.gov