MedTrace Logo

Immune and Endocrine Function in Post-Traumatic Stress Disorder

NCT00100490 · Status: COMPLETED · Type: OBSERVATIONAL

Last updated 2009-01-21

No results posted yet for this study

Summary

This is a study investigating immune function and relationships to the hypothalamic-pituitary-adrenal (HPA) axis in Post-traumatic stress disorder (PTSD) compared to controls without PTSD. The study involves 99 adult veterans and civilian subjects over a 3 year period. The study involves measuring immune and neuroendocrine parameters from blood samples obtained before and after a dexamethasone suppression test. The aim of the study is to determine whether immune alterations exist in PTSD and whether the immune-HPA axis interactions in this disorder are different from non-PTSD subjects with the future aim of studying whether immune dysregulation in PTSD may be linked to the increased risk for medical and psychiatric comorbidity in this population.

Conditions

  • Post-Traumatic Stress Disorders

Sponsors & Collaborators

Principal Investigators

  • Rachel Yehuda, Ph.D.

  • Lloyd Mayer, M.D.

  • Esther Sternberg, M.D.

  • Bruce McEwen, Ph.D.

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
1999-10-31
Completion
2002-09-30

Countries

  • United States

Study Locations

More Related Trials

Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00100490 on ClinicalTrials.gov