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An Evaluation of Two PTSD Assessments in an Active Duty and Military Veteran Sample

NCT04180930 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 950

Last updated 2025-01-23

No results posted yet for this study

Summary

Given the high prevalence of post-traumatic stress disorder (PTSD) in veterans and active duty military, the focus of this research study is to test the reliability of two new PTSD assessments, the Clinician Administered PTSD Scale for DSM-5 (CAPS-5) and the PTSD Symptom Scale Interview for DSM-5 (PSSI-5) and compare the results between the two new assessments and the previous "gold standard", the Clinician Administered PTSD Scale for DSM-IV (CAPS-IV). Biomarkers believed to be related to PTSD (e.g., biofluid biomarkers, cognitive and physiological markers, and neural activity as measured by EEG) will be collected to inform targeted interventions in specific groups of patients and other large-scale biomarker discovery efforts in the field. Participants will be 950 male and female active duty military and veterans ages 18 or older who have been exposed to at least one traumatic event.

Conditions

  • Stress Disorders, Post-Traumatic

Interventions

DIAGNOSTIC_TEST

CAPS-5

Clinician Administered PTSD Scale for DMS-5

DIAGNOSTIC_TEST

PSSI-5

PTSD Symptom Scale Interview for DSM-5

DIAGNOSTIC_TEST

CAPS-IV

Clinician Administered PTSD Scale for DSM-IV

Sponsors & Collaborators

  • U.S. Army Medical Research and Development Command

    lead FED

Principal Investigators

  • Kathleen M Chard, PhD · Cincinnati VA Medical Center, University of Cincinnati

  • Brian Marx, PhD · National Center for PTSD at VA Boston Healthcare System

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-04-15
Primary Completion
2025-06-30
Completion
2025-06-30

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04180930 on ClinicalTrials.gov