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Air Pollution and Implantable Cardioverter Defibrillators

NCT00015574 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 500

Last updated 2006-09-04

No results posted yet for this study

Summary

Community based studies have shown increased cardiovascular mortality associated with acute exposures to particulate air pollution. Electrocardiographic changes have also been reported in animals exposed to particles in controlled conditions. We have hypothesized that cardiovascular patients may experience life-threatening arrhythmias associated with particulate air pollution episodes. Implanted cardioverter defibrillator (ICD) devices continuously monitor the heart rhythm, and on detecting arrhythmias can initiate interventions. These devices provide a passive, continuous monitor of cardiac arrhythmias. We are assessing the association between community exposures to air pollution measured by ambient monitors and these cardiac arrhythmias detected by implanted cardioverter defibrillator devices.

Conditions

  • Arrythmias

Sponsors & Collaborators

  • Tufts Medical Center

    collaborator OTHER

  • National Institute of Environmental Health Sciences (NIEHS)

    lead NIH

Principal Investigators

  • Douglas Dockery, ScD · Harvard School of Public Health (HSPH)

Eligibility

Min Age
0 Years
Max Age
90 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
1998-09-30
Completion
2004-09-30

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00015574 on ClinicalTrials.gov