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Reducing Particulate Matter-associated Cardiovascular Health Effects for Seniors

NCT04103346 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 52

Last updated 2026-01-16

Study results available
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Summary

Exposure to fine particulate matter (PM2.5) air pollution is an established risk factor for cardiovascular (CV) morbidity.

Conditions

  • Cardiometabolic Health

Interventions

OTHER

air filtration with air purifier with hepa filter

long-term (4 week) air filtration with the Holmes HAP8650B-NU-1 air purifier in the residence of low-income seniors impacted by roadway pollutants.

OTHER

sham

air purifier running with air filter removed

Sponsors & Collaborators

Principal Investigators

  • Robert Brook, MD · Wayne State University

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
TRIPLE
Model
CROSSOVER

Eligibility

Min Age
60 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2020-02-24
Primary Completion
2024-11-01
Completion
2024-11-01

Countries

  • United States

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04103346 on ClinicalTrials.gov