MedTrace Logo

The Cardiovascular Benefits of Reducing Personal Exposure to Air Pollution

NCT00809432 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 15

Last updated 2008-12-17

No results posted yet for this study

Summary

Exposure to air pollution is an important risk factor for cardiovascular morbidity and mortality, and is associated with increased blood pressure, reduced heart rate variability, endothelial dysfunction and myocardial ischaemia. The study objectives were to assess the potential cardiovascular benefits of reducing personal particulate air pollution exposure by wearing a facemask in healthy volunteers.

Conditions

  • Blood Pressure
  • Heart Rate Variability

Interventions

DEVICE

Face mask (Dust Respirator)

Subjects to wear a simple face mask for 24 hours prior to the study day and the 24 hours of the study day. They will be instructed to wear the mask as much as possible when indoors and at all times when outdoors.

OTHER

No Face mask

Subjects will not wear a face mask to reduce their personal exposure to air pollution

Sponsors & Collaborators

  • Peking Union Medical College

    collaborator OTHER

  • University of Edinburgh

    lead OTHER

Principal Investigators

  • Jeremy P Langrish, MB BCh MRCP · University of Edinburgh

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
CROSSOVER

Eligibility

Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2008-08-31
Primary Completion
2008-08-31
Completion
2008-08-31

Countries

  • China

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00809432 on ClinicalTrials.gov