Filgrastim and Chemotherapy Followed by Peripheral Stem Cell Transplant in Treating Patients With Hodgkin's Lymphoma or Non-Hodgkin's Lymphoma
NCT00005985 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 213
Last updated 2017-11-29
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining chemotherapy with peripheral stem cell transplant may allow the doctor to give higher doses of chemotherapy drugs and kill more cancer cells. Colony-stimulating factors such as filgrastim may increase the number of immune cells found in bone marrow or peripheral blood and may help a person's immune system recover from the side effects of chemotherapy.
PURPOSE: This phase II trial is studying how well giving filgrastim together with chemotherapy and peripheral stem cell transplant works in treating patients with Hodgkin's lymphoma or non-Hodgkin's lymphoma.
Conditions
Interventions
- BIOLOGICAL
- DRUG
-
carmustine
- DRUG
- DRUG
- DRUG
- DRUG
-
etoposide
- DRUG
-
mitoxantrone hydrochloride
- PROCEDURE
-
peripheral blood stem cell transplantation
- RADIATION
-
radiation therapy
Sponsors & Collaborators
-
Masonic Cancer Center, University of Minnesota
lead OTHER
Principal Investigators
-
Daniel J. Weisdorf, MD · Masonic Cancer Center, University of Minnesota
Study Design
- Purpose
- TREATMENT
- Masking
- NONE
Eligibility
- Max Age
- 70 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2000-08-31
- Primary Completion
- 2007-02-28
- Completion
- 2007-02-28
Countries
- United States
Study Locations
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