Peripheral Stem Cell Transplantation Plus Combination Chemotherapy in Treating Patients With Low-Grade Non-Hodgkin's Lymphoma or Chronic Lymphocytic Leukemia

NCT00003402 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 35

Last updated 2019-10-17

No results posted yet for this study

Summary

RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining chemotherapy with peripheral stem cell transplantation may allow the doctor to give higher doses of chemotherapy drugs and kill more cancer cells.

PURPOSE: Phase II trial to study the effectiveness of peripheral stem cell transplantation plus combination chemotherapy in treating patients who have low-grade non-Hodgkin's lymphoma or chronic lymphocytic leukemia.

Conditions

Interventions

DRUG: carmustine
DRUG: cisplatin
DRUG: cyclophosphamide
DRUG: dexamethasone
DRUG: etoposide
DRUG: melphalan
DRUG: paclitaxel
PROCEDURE: bone marrow ablation with stem cell support
PROCEDURE: peripheral blood stem cell transplantation

Sponsors & Collaborators

University of Maryland Greenebaum Cancer Center
collaborator OTHER
University of Maryland, Baltimore
lead OTHER

Principal Investigators

Barry R. Meisenberg, MD · University of Maryland Greenebaum Cancer Center

Study Design

Purpose: TREATMENT

Eligibility

Min Age: 18 Years
Max Age: 70 Years
Sex: ALL
Healthy Volunteers: No

Timeline & Regulatory

Start: 1999-01-31
Primary Completion: 2002-12-31
Completion: 2002-12-31

Countries

United States

Study Locations

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Entities

Drugs

Diseases