Biological Therapies Following Peripheral Stem Cell Transplantation in Treating Patients With Non-Hodgkin's Lymphoma, Hodgkin's Disease, or Advanced Breast Cancer
NCT00005993 · Status: TERMINATED · Phase: PHASE1 · Type: INTERVENTIONAL
Last updated 2017-11-29
Summary
RATIONALE: Interleukin-2 may stimulate a person's white blood cells to kill cancer cells. Filgrastim and stem cell factor may increase the number of immune cells found in bone marrow or peripheral blood and may help a person's immune system recover from the side effects of cancer therapy. Peripheral stem cell transplantation may be able to replace immune cells that were destroyed by therapy used to kill cancer cells.
PURPOSE: Phase I trial to study the effectiveness of interleukin-2 and stem cell factor following peripheral stem cell transplantation in treating patients who have non-Hodgkin's lymphoma, Hodgkin's disease, or advanced breast cancer.
Conditions
Interventions
- DRUG
-
aldesleukin
- DRUG
- DRUG
-
recombinant human stem cell factor
- PROCEDURE
-
peripheral blood stem cell transplantation
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH -
Masonic Cancer Center, University of Minnesota
lead OTHER
Principal Investigators
-
Linda J. Burns, MD · Masonic Cancer Center, University of Minnesota
Study Design
- Purpose
- TREATMENT
Eligibility
- Min Age
- 18 Years
- Max Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 1999-05-31
- Primary Completion
- 2005-07-31
- Completion
- 2005-07-31
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