Study of Homocysteine Metabolism in Homocystinuria
NCT00004356 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 60
Last updated 2005-06-24
Summary
OBJECTIVES: I. Determine basal and postmethionine plasma homocysteine in patients with premature vascular disease, cystathionine beta-synthase (CBS) or methylenetitrahydrofolate reductase (MTHFR) deficiency, and in obligate heterozygotes for CBS or MTHFR.
II. Determine whole-body homocysteine metabolic rates with isotopically-labeled methionine.
Conditions
- Homocystinuria
Sponsors & Collaborators
-
University of California, San Diego
collaborator OTHER -
National Center for Research Resources (NCRR)
lead NIH
Principal Investigators
-
Bruce Barshop · University of California, San Diego
Eligibility
- Min Age
- 0 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 1995-02-28
- Completion
- 2000-10-31
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