Prevention of Graft-Versus-Host Disease in Patients Undergoing Bone Marrow Transplantation
NCT00003538 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL
Last updated 2014-05-02
Summary
RATIONALE: Bone marrow transplantation may be able to replace immune cells that were destroyed by chemotherapy or radiation therapy used to kill tumor cells. Sometimes the transplanted cells can make an immune response against the body's normal tissues. Stem cells that have been treated in the laboratory to remove lymphocytes may prevent this from happening.
PURPOSE: Clinical trial to prevent graft-versus-host disease in patients undergoing bone marrow transplantation.
Conditions
Interventions
- BIOLOGICAL
-
graft versus host disease prophylaxis/therapy
- PROCEDURE
-
allogeneic bone marrow transplantation
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH -
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
lead OTHER
Principal Investigators
-
Richard J. Jones, MD · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Study Design
- Purpose
- SUPPORTIVE_CARE
Eligibility
- Max Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 1997-03-31
- Primary Completion
- 2004-05-31
- Completion
- 2004-05-31
Countries
- United States
Study Locations
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