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In-Vitro Studies in Depletion of Haplotype Mismatched Alloreactive T Cells

NCT00731705 · Status: WITHDRAWN · Type: OBSERVATIONAL

Last updated 2014-09-19

No results posted yet for this study

Summary

The doctors in the Bone Marrow Transplant Service at the Indiana University Cancer Center are working to better understand how the immune cells that cause graft-versus-host disease (a major complication of stem cell transplantation in which the donor immune cells attack the patient's organs) can be selectively removed from the graft, leaving other immune cells that fight infections.

Conditions

Interventions

PROCEDURE

collection of peripheral blood and apheresis samples

Sixty mL of peripheral blood will be collected from consenting eligible donors. Additionally, after the laboratory techniques have been fully evaluated, leukopheresis samples will also be collected.

Sponsors & Collaborators

  • National Institutes of Health (NIH)

    collaborator NIH

  • Indiana University School of Medicine

    lead OTHER

Principal Investigators

  • Sherif Farag, MD, PhD · Indiana University Melvin and Bren Simon Cancer Center

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2007-01-31
Primary Completion
2010-01-31
Completion
2010-01-31

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Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00731705 on ClinicalTrials.gov