T-Cell Depletion in Unrelated Donor Marrow Transplantation
NCT00000591 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL
Last updated 2016-04-15
Summary
To determine if a reduction in morbidity and mortality from acute and chronic graft versus host disease (GvHD) can be achieved through use of T-cell depletion techniques without a counterbalancing increase in relapse of leukemia in patients receiving an unrelated donor marrow transplant.
Conditions
- Bone Marrow Transplantation
- Graft vs Host Disease
- Immunologic Diseases
- Leukemia
- Myelodysplastic Syndromes
Interventions
- PROCEDURE
-
lymphocyte depletion
Sponsors & Collaborators
-
National Heart, Lung, and Blood Institute (NHLBI)
lead NIH
Principal Investigators
-
Shelly Carter · The Emmes Company, LLC
-
John Wagner · University of Minnesota
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
Eligibility
- Min Age
- 1 Year
- Max Age
- 55 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 1993-11-30
- Completion
- 2005-02-28
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