Combination Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating Patients With Chronic Myelogenous Leukemia
NCT00002674 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 30
Last updated 2010-04-02
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Bone marrow transplantation may be able to replace immune cells that were destroyed by chemotherapy used to kill cancer cells.
PURPOSE: Phase II trial to study the effectiveness of combination chemotherapy followed by G-CSF and peripheral stem cell transplantation in treating patients with chronic myelogenous leukemia.
Conditions
Interventions
- BIOLOGICAL
- DRUG
- DRUG
-
etoposide
- DRUG
-
hydroxyurea
- DRUG
-
mitoxantrone hydrochloride
- PROCEDURE
-
peripheral blood stem cell transplantation
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH -
Fred Hutchinson Cancer Center
lead OTHER
Principal Investigators
-
Leona A. Holmberg, MD, PhD · Fred Hutchinson Cancer Center
Study Design
- Purpose
- TREATMENT
Eligibility
- Min Age
- 17 Years
- Max Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 1994-10-31
- Primary Completion
- 2000-03-31
- Completion
- 2000-03-31
Countries
- United States
Study Locations
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